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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKAR1A
All Species:
32.42
Human Site:
S77
Identified Species:
50.95
UniProt:
P10644
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10644
NP_002725.1
381
42982
S77
K
A
G
T
R
T
D
S
R
E
D
E
I
S
P
Chimpanzee
Pan troglodytes
XP_511647
260
29299
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537577
381
43019
S77
K
A
S
S
R
A
D
S
R
E
D
E
I
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBC7
381
43167
S77
K
T
G
I
R
T
D
S
R
E
D
E
I
S
P
Rat
Rattus norvegicus
P09456
381
43076
S77
K
S
G
I
R
T
D
S
R
E
D
E
I
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509586
626
69567
S321
K
A
S
S
R
S
D
S
R
E
D
E
I
S
P
Chicken
Gallus gallus
Q5ZM91
382
43332
S77
K
S
G
S
R
S
D
S
R
E
D
E
I
S
P
Frog
Xenopus laevis
NP_001085084
381
43157
S76
K
S
G
S
R
S
D
S
R
E
D
E
I
S
P
Zebra Danio
Brachydanio rerio
NP_001017732
379
43009
S76
K
A
S
S
R
S
D
S
R
E
D
E
V
S
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P16905
376
42221
C75
Q
V
I
S
P
D
D
C
E
D
L
S
P
M
P
Honey Bee
Apis mellifera
XP_396167
372
41646
R86
Q
Q
G
P
Q
V
P
R
R
R
G
G
I
S
A
Nematode Worm
Caenorhab. elegans
P30625
366
41449
V73
A
D
D
D
D
I
I
V
E
P
P
K
R
S
G
Sea Urchin
Strong. purpuratus
Q26619
369
41770
S81
N
R
Y
A
R
R
K
S
V
C
A
E
K
Y
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P07278
416
47201
T125
A
Q
E
E
Q
Q
H
T
R
E
K
T
S
T
P
Red Bread Mold
Neurospora crassa
Q01386
385
42138
A80
R
Q
P
D
D
F
P
A
H
Y
N
L
G
R
R
Conservation
Percent
Protein Identity:
100
68.2
N.A.
97.9
N.A.
96.8
97.3
N.A.
58.7
92.4
92.6
91.5
N.A.
71.3
74
57.7
39.3
Protein Similarity:
100
68.2
N.A.
98.1
N.A.
97.3
98.4
N.A.
60
96
95.8
95.8
N.A.
81.6
85.3
73.4
56.9
P-Site Identity:
100
0
N.A.
80
N.A.
86.6
86.6
N.A.
80
80
80
73.3
N.A.
13.3
26.6
6.6
20
P-Site Similarity:
100
0
N.A.
86.6
N.A.
86.6
93.3
N.A.
93.3
100
100
93.3
N.A.
33.3
40
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.2
34
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.7
52.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
27
0
7
0
7
0
7
0
0
7
0
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
7
0
7
0
0
0
0
0
% C
% Asp:
0
7
7
14
14
7
60
0
0
7
54
0
0
0
7
% D
% Glu:
0
0
7
7
0
0
0
0
14
60
0
60
0
0
0
% E
% Phe:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
40
0
0
0
0
0
0
0
7
7
7
0
7
% G
% His:
0
0
0
0
0
0
7
0
7
0
0
0
0
0
0
% H
% Ile:
0
0
7
14
0
7
7
0
0
0
0
0
54
0
0
% I
% Lys:
54
0
0
0
0
0
7
0
0
0
7
7
7
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
7
7
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% M
% Asn:
7
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% N
% Pro:
0
0
7
7
7
0
14
0
0
7
7
0
7
0
67
% P
% Gln:
14
20
0
0
14
7
0
0
0
0
0
0
0
0
0
% Q
% Arg:
7
7
0
0
60
7
0
7
67
7
0
0
7
7
7
% R
% Ser:
0
20
20
40
0
27
0
60
0
0
0
7
7
67
0
% S
% Thr:
0
7
0
7
0
20
0
7
0
0
0
7
0
7
0
% T
% Val:
0
7
0
0
0
7
0
7
7
0
0
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
0
0
0
0
0
7
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _